People with atypical hemolytic uremic syndrome (aHUS) who start treatment with Soliris (eculizumab) or Ultomiris (ravulizumab) — both marketed by Alexion — generally use fewer healthcare resources, according to a new U.S. study. Indeed, rates of insurance claims for aHUS patients starting on either therapy dropped substantially…
News
Reduced capillary density and capillary abnormalities were identified in people with atypical hemolytic uremic syndrome (aHUS) using a nailfold dermoscopy, a study in Turkey reports. Nailfold dermoscopy is a noninvasive technique that lets doctors evaluate the small blood vessels (capillaries) in the nail fold. These observations suggest the technique…
Plasma exchange combined with rituximab, an immunosuppressant, might prevent atypical hemolytic uremic syndrome (aHUS) from coming back after a kidney transplant, according to a small study from India. The study, “Kidney Transplant Outcomes in Patients with Atypical Hemolytic Uremic Syndrome,” was published in Transplantation Proceedings. aHUS is…
Treatment with the drug Soliris (eculizumab) for atypical hemolytic uremic syndrome (aHUS) initially failed to ease the symptoms of a middle-age woman with AHUS and multiorgan involvement, a case study reported. Higher Soliris doses eventually eased disease symptoms in all organs except the kidneys, which had to be replaced…
A synthetic psychoactive drug was identified as the trigger that led to the onset of atypical hemolytic uremic syndrome (aHUS) in a 37-year-old man who was genetically prone to develop the condition, a case study in Croatia reported. “Our case is the first report of aHUS with proven ……
Pregnancy was identified as the trigger event for atypical hemolytic uremic syndrome (aHUS) that resulted in kidney damage for a genetically predisposed woman in her mid-20s, a U.S. case study reported. The patient had a clinical history of poorly managed high blood pressure and often failed to comply with…
A 38-year-old man developed atypical hemolytic uremic syndrome (aHUS) and end-stage kidney disease (ESKD) after receiving his first dose of AstraZeneca’s COVID-19 vaccine, according to a case report. The patient was admitted to a hospital in Saudi Arabia one week after being vaccinated. Tests revealed changes in blood parameters…
For the first time in South Korea, a patient who developed atypical hemolytic uremic syndrome (aHUS) after undergoing a kidney transplant was successfully treated with Soliris (eculizumab). “We report the first successful case of aHUS treatment in a kidney transplant recipient with early use of [Soliris] in South…
Preventive treatment with Soliris (eculizumab) before surgery dramatically improved kidney transplant outcomes in people with atypical hemolytic uremic syndrome (aHUS), according to a recent study. One year after the surgeries, 97% of transplanted kidneys still functioned in Soliris-treated patients. In those who did not receive preventive treatment, that…
A woman in her mid-30s with a twin pregnancy was diagnosed with atypical hemolytic uremic syndrome (aHUS) after she experienced complications following delivery by cesarean section. Two healthy girls were born, and the mother’s condition improved following treatment. But researchers noted that “this report underlines how crucial it is…
Recent Posts
- How inflammation from multiple conditions led to an eye emergency
- Early treatment critical in aHUS to prevent lasting kidney damage
- I struggle daily with deconditioning from my multiple illnesses
- Complement inhibitors show edge over plasma at stopping aHUS relapses
- Boy’s kidney issues resolve after Soliris treatment: Case report
- I’m learning to say, ‘There’s always tomorrow’ when I’m feeling guilty
- Rare aHUS after kidney transplant successfully treated with Soliris
- Study describes ‘unusual trilogy’ of aHUS, Fabry disease, heart disorder
- My complicated health journey now includes post-exertional malaise
- Soliris part of strategy for complex kidney transplant in aHUS case