Colombian children seen for the first time for atypical hemolytic uremic syndrome (aHUS) had a high frequency of disease manifestations involving organs other than the kidneys, with two-thirds showing signs of lung involvement, a study reports. Their prognosis was worse than reported in previous studies, with more than half…
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At the onset of atypical hemolytic uremic syndrome (aHUS) among children in India, high levels of antibodies against a complement protein called factor B were tied to disease severity, a new study by researchers in New Delhi revealed. Importantly, all pediatric patients with genetic mutations associated with aHUS did…
The case of a 69-year-old-woman with atypical hemolytic uremic syndrome (aHUS) who carried mutations in the CFI and the DGKE genes that hadn’t previously been associated with the disease, was described in a recent report. The woman responded well to treatment with…
An 8-year-old girl was diagnosed with a rare case of atypical hemolytic uremic syndrome (aHUS) and cardiac arrhythmias, or abnormal heartbeats, according to a recent report from Turkey. While known for its damage to the kidneys, aHUS can affect the heart, with cases of heart muscle disease and heart failure…
In cases of atypical hemolytic uremic syndrome (aHUS) that develop following pregnancy and childbirth, getting an early diagnosis is important for appropriate and timely treatment and better outcomes, a case report highlights. “A prompt and accurate diagnosis is critical in these patients to initiate early treatment, which can significantly…
An 11-year-old boy was diagnosed with atypical hemolytic uremic syndrome (aHUS) after having symptoms that included a hard-to-treat headache, low appetite, fever, and shortness of breath, according to a case report from Nepal. His symptoms underscore the need for a “multidisciplinary approach … for aHUS due to its rarity…
A COVID-19 vaccine may have triggered the development of two autoimmune diseases, atypical hemolytic uremic syndrome (aHUS) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), which are associated with damage to small blood vessels and the kidneys, in a 67-year-old man three weeks after vaccination, according to a case…
The case of a woman who developed atypical hemolytic uremic syndrome (aHUS) following pregnancy highlights the importance of an early diagnosis and prompt treatment of the disease. As many as 20% of aHUS cases occur in people who are pregnant or have just given birth, referred to as…
Treatment with Soliris (eculizumab) helped about half of the children diagnosed with atypical hemolytic uremic syndrome (aHUS) after they received a stem cell transplant, according to a small study. Among 13 patients who started taking Soliris, seven survived and saw their disease-associated biomarkers normalize. Six died due to complications…
A team of five experts from across Spain got together to reach a consensus on a set of recommendations for how to best manage atypical hemolytic uremic syndrome (aHUS) in adults. The consensus offers guidance for doctors with less experience in managing the disease. It covers the entire patient…
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