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Two brothers with atypical hemolytic uremic syndrome (aHUS) were also diagnosed with a rare inherited metabolic disorder after doctors in Turkey investigated the unusual symptom of urine that repeatedly turned black, according to a case report. The siblings, ages 24 and 19, had experienced several episodes of aHUS, a…

People with atypical hemolytic uremic syndrome (aHUS) consider treatment effectiveness and safety as top priorities when choosing medications, an international survey showed. Most patients also said they would prefer oral therapies and less frequent dosing. The findings, based on responses from 122 patients, revealed a substantial burden from treatment-related…

Kidney transplants can result in favorable outcomes for people with atypical hemolytic uremic syndrome (aHUS) in India, even when the disease returns after transplant, provided patients are evaluated before surgery and treated for complications soon afterward if they occur. That’s according to a new study from the Asian nation…

A woman with a history of blood abnormalities and kidney problems during and after pregnancies was eventually diagnosed with postpartum-triggered atypical hemolytic uremic syndrome (aHUS) in a case study. After aHUS was strongly suspected, she began Soliris (eculizumab) treatment and ultimately achieved complete remission. The researchers recommended that…

Plasma exchange helped ease severe bluish discoloration and pain in the fingers and toes of a 3-year-old boy with atypical hemolytic uremic syndrome (aHUS) that persisted despite treatment with Soliris (eculizumab). During the procedure, the liquid part of the blood, or plasma, is removed and replaced by that of…

A nurse-led care team in China successfully treated an 8-month-old boy with atypical hemolytic uremic syndrome (aHUS) who developed blistering skin wounds that hardened with calcium deposits. In addition to normalizing his kidney function, the team used a staged, moisture-based wound-care approach that healed his wound in about seven…

A young Asian woman with a genetic blood disease developed atypical hemolytic uremic syndrome (aHUS) after childbirth, leading clinicians to treat the rare case with hemodialysis, in which machines are used to clean a person’s blood, and supportive care. The researchers reported that the woman, who was living with…

Treatment with Ultomiris (ravulizumab) led to rapid blood and kidney recovery in a 12-year-old girl with atypical hemolytic uremic syndrome (aHUS) associated with a rare genetic mutation, according to a case report. The girl developed acute kidney failure, thrombocytopenia (low counts of platelets, small cell fragments that help…

Factor XIII (FXIII) activity was lower in samples collected during acute episodes of atypical hemolytic uremic syndrome (aHUS), while levels of one of its subunits, FXIII-B, were higher in samples collected during remission, suggesting FXIII-B may serve as a marker of disease activity. “Free FXIII-B emerges as a promising…

Developing atypical hemolytic uremic syndrome (aHUS) complicated the recovery of a baby boy with typical hemolytic uremic syndrome (HUS) — a related condition caused by an infection — but prompt treatment with the approved infusion med Soliris (eculizumab) led to a complete recovery. That’s according to a case…