Author Archives: Vanda Pinto PhD

Boy With aHUS Develops Severe COVID-19 Infection, Case Study Reports

An 11-year-old boy with atypical hemolytic uremic syndrome (aHUS) became severely ill following infection with SARS-CoV-2, the virus that causes COVID-19, according to a recent case report. “Our study [shows] that severe SARS-COV-2 infection can be developed in pediatric patients with co-existing [aHUS],” the author wrote. The report, “…

New Mutation in TSEN2 Gene Associated With aHUS, Study Finds

A newly identified mutation in the TSEN2 gene that causes craniofacial abnormalities, intellectual and developmental disabilities, as well as atypical hemolytic uremic syndrome (aHUS), was found in six children, a genetic study shows. Based on these observations, scientists proposed naming the new syndrome “TRACK” which stands for TSEN2-related atypical…

Pregnancy Generally Safe for Women With aHUS, Study Suggests

If closely monitored, women with atypical hemolytic uremic syndrome (aHUS) can have successful and uncomplicated pregnancies, including those on dialysis or patients who had undergone a kidney transplant, according to a new study. Additionally, researchers confirmed that patients can safely and effectively be treated with Soliris (eculizumab), an…

Severe COVID-19 Suspected as Trigger of aHUS in 3-year-old Girl

COVID-19 appears to have triggered an exaggerated immune response in a toddler, leading to the development of atypical hemolytic uremic syndrome (aHUS) in the absence of disease-relevant mutations, scientists reported. “This is a rare case report of a child with COVID-19 developing HUS. Since HUS developed following a COVID-19…