Boosting Cell Stress Response May Be Therapeutic Approach in aHUS
Endothelial cells, or those that line blood vessels, are functionally abnormal in people with atypical hemolytic uremic syndrome (aHUS) associated with antibodies against complement factor H or CFH, according to a small study using patient-derived cells. Notably, these intrinsic defects were associated with reduced activation of the p38 MAPK…