News

Plasma exchange therapy managed aHUS in elderly man: Report

Plasma exchange therapy successfully managed atypical hemolytic uremic syndrome (aHUS) triggered by pancreas inflammation in a 72-year-old man, according to a case report from China. However, discontinuation of plasma exchange and a transition to hemodialysis — a treatment used to remove waste and excessive fluid from the blood when…

Plasma exchange therapy, Soliris manage aHUS in boy: Report

Plasma exchange therapy followed by treatment with Soliris (eculizumab) was effective at managing atypical hemolytic uremic syndrome (aHUS) in a boy in China. The case was described in the report, “Plasma exchange combined with eculizumab in the management of atypical hemolytic uremic in pediatric patients:…

Surgery to remove gallstones can give rise to aHUS: Study

Atypical hemolytic uremic syndrome (aHUS) can be a rare complication of a procedure to remove gallstones, according to a report in the U.S. that describes the case of a teenage girl who developed the condition secondary to post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. The study, “Atypical hemolytic…

Plasma exchange therapy, Ultomiris manage woman’s aHUS

Early plasma exchange therapy followed by Ultomiris  (ravulizumab) treatment successfully managed atypical hemolytic uremic syndrome (aHUS) in an 83-year-old woman, according to a report from Japan. The woman started showing symptoms of aHUS after a bone fracture. Genetic testing revealed she had a mutation in the CFI gene,…

Report aims to help distinguish aHUS disease vs. HELLP syndrome

The pregnancy-related complication HELLP syndrome — fully known as hemolysis, elevated liver enzymes, and low platelets syndrome, which causes high blood pressure and organ damage — is sometimes confused with atypical hemolytic uremic syndrome, or aHUS, a rare disease in which kidney dysfunction persists for a long time, especially…

Soliris reduces kidney risks from pregnancy-associated aHUS: Study

Soliris (eculizumab) largely reduces the risk of long-term kidney problems in women who develop atypical hemolytic uremic syndrome (aHUS) during or after pregnancy, a meta-analysis study has found. “This analysis highlights the severe kidney and pregnancy outcomes associated with [pregnancy-associated aHUS],” researchers wrote, noting Soliris treatment is beneficial…

Interactive e-book aims to help children better understand aHUS

An interactive electronic storybook, or e-book, designed to help children with atypical hemolytic uremic syndrome (aHUS) better understand their rare disease, has been launched by Alexion, AstraZeneca Rare Disease, which markets two aHUS therapies. Called “Revealing the Secrets of aHUS,” the fantasy e-book uses imaginative play to…