Marisa Wexler, MS,  senior science writer—

Inflammation of the pancreas, known as pancreatitis, can occur alongside the rare disease atypical hemolytic uremic syndrome (aHUS) — as a team of researchers from China highlighted in a new report outlining the case of a young woman found to have both conditions. The woman sought medical attention due…

Soliris (eculizumab) helped control atypical hemolytic uremic syndrome (aHUS) in a patient whose symptoms included seizures and signs of neurological damage, according to a case report. The researchers said the case points to “the importance of timely diagnosis and treatment of aHUS as well as the…

Plasma exchange therapy followed by treatment with Soliris (eculizumab) was effective at managing atypical hemolytic uremic syndrome (aHUS) in a boy in China. The case was described in the report, “Plasma exchange combined with eculizumab in the management of atypical hemolytic uremic in pediatric patients:…

Epysqli (eculizumab-aagh), a biosimilar of Soliris (eculizumab), is now available for patients in the U.S., according to an announcement from Samsung Bioepis and Teva Pharmaceuticals. The biosimilar is authorized to treat people with atypical hemolytic uremic syndrome (aHUS), as well as paroxysmal nocturnal hemoglobinuria, and…

A woman with lupus in her early 30s, who developed atypical hemolytic uremic syndrome (aHUS) after pregnancy, was not suspected of having the rare condition until five days after her baby’s birth, which resulted in her not receiving the correct treatment, according to a case report from researchers in…

Atypical hemolytic uremic syndrome (aHUS) can be a rare complication of a procedure to remove gallstones, according to a report in the U.S. that describes the case of a teenage girl who developed the condition secondary to post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. The study, “Atypical hemolytic…

Disease manifestations that affect the brain, such as seizures, are relatively common with atypical hemolytic uremic syndrome (aHUS), as are digestive symptoms and heart-related problems, a study finds. The study, “Extrarenal manifestations of atypical hemolytic uremic syndrome: a systematic review and meta-analysis,” was published in Pediatric…

A weight-based regimen for administering Soliris (eculizumab) in people with atypical hemolytic uremic syndrome (aHUS) may allow patients to reach therapeutic levels of the medication with fewer infusions, saving time and money. “We suggest to introduce this dosing schedule as the standard of care to improve therapeutic success…

Changes in platelet counts over the first two weeks on Ultomiris (ravulizumab-cwvz) in people with atypical hemolytic uremic syndrome (aHUS) may help predict the patients’ long-term response to such treatment, according to a new study. An analysis found that patients’ early platelet responses were linked to kidney improvements at…

A girl in China had atypical hemolytic uremic syndrome (aHUS) and accompanying protein-losing enteropathy (PLE), a condition in which there is an excessive loss of proteins through the gastrointestinal tract. Treatment with Soliris (eculizumab) resolved both her aHUS-related kidney disease and PLE, according to a report. “Our case…